The newsletter from the JNHA, the official journal of the IAGG, has reached the office of the Organizing Committee for the 20th IAGG World Congress of Gerontology and Geriatrics and we open it to the homepage visitors. Attention and more participation are requested.
The JNHA is the official journal of the IAGG (International Association of Gerontology and Geriatrics, www.iagg.com.br), the IANA (International Academy on Nutrition and Aging, www.healthandage.com/html/min/iananda/content/about.htm), the EUGMS (European Union Geriatric Medicine Society, www.eugms.org)
In this issue
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· Clinical trials and aging: a new section for the JNHA
· JNHA n° 2, vol. 12, 2008, contents
· JNHA n° 3, vol. 12, 2008, contents
· All JNHA papers until 2008 are free access online and at the IAGG web site links
· Forthcoming IAGG, IANA and EUGMS congress, workshop
. IANA 2008 Symposium on Exercise, Cognitive Decline; Frailty and Sarcopenia Clinical Trials (Albuquerque,
August, 1st and 2nd, 2008)
. The 1st conference clinical trials on Alzheimer’s disease (CTAD)
. The IAGG world meeting Paris, 5-9 July 2009
. 5th Congress of the EUGMS: Geriatric medicine in a time of generational shift (Copenhagen, 3-6 September 2008)
· The I.A.N.A. Task Force on Frailty assessment of older people in clinical practice
I CLINICAL TRIALS AND AGING: A NEW SECTION FOR THE JNHA: Editor in Chief S. Gauthier, McGill University, Montral, Canada. S. Gauthier, MCSA Alzheimer's Disease Research Unit, McGill Centre for Studies in Aging, Quebec, Canada
A Clinical Trial Section is required in the JNHA to answer many questions about interventions in nutrition, health and aging. We are now facing the limitations of randomized clinical trials (RCT) that follow rigidly regulatory “guidelines” and there is a pressing need for a revitalization of the field of RCT in age-associated disorders.
This Section will encourage submissions of manuscripts that explore novel trial designs and outcomes, both cognitive and non-cognitive, and revisit traditional enrollment criteria. Both pharmacologic and non-pharmacologic interventions can be submitted. The full range of normal aging, asymptomatic at risk populations, mild impairment and dementia can be studied with appropriate designs and outcomes. Ethical issues in RCT at these different clinical states should be considered.
We encourage new hypothesis to be proposed and a “letters to the Editor” sub-section will facilitate exchanges among readers of the JNHA, possibly leading to new RCT bridging investigators across countries.
The first two articles (1, 2) of this Section are very representative of its intent: pooling resources through a uniform data set, a model that can be expanded to non-European nations, and a review of the causes of the under-representation of older people in clinical trials.
An international panel of Associate Editors will be assisting me in bringing this new Section to its full potential, hopefully for the benefit of our patients. They include Dr Susan Abu-Shakra (USA), Drs Michael Borrie (Canada), Dr Bruno Dubois (France), Dr Marco Pahor (USA), Dr Dennis Seow (Singapore).
1. D.W. Habicht, M.D. Witham, M.E.T. McMurdo. The under-representation of older people in clinical trials: barriers and potential solutions. J Nutr Health Aging. 2008;12(3): 194-196; 2. G. Abellan van Kan, A. Sinclair, S. Andrieu, M. Olde Rikkert, G. Gambassi, B. Vellas on behalf of the GerontoNet Collaboration. The Geriatric Minimum Data Set for Clinical Trials (GMDS). J Nutr Health Aging. 2008;12(3): 197-200
II - JNHA N° 2, Vol 12, 2008 contents
Editorial: Longevity, Health and Well-being. Issues in Aging in North America, N. Keating, and al. (Canada)
1. Nutrition: Dietary Intake of Older Patients in Hospital and at Home: The Validity of Patient Kept Food Diaries,S.E. Gariballa, and al. (United Arab Emirates, United Kingdom ; Factors Associated with Errors in Self-Reported Height and Weight in Older Adults, N.R. Sahyoun, and al. (USA); Which are the Most Efficient Items of Mini Nutritional Assessment in Multimorbid Patients? S. Hengstermann and al. (Germany)
2. Clinical Neurosciences: Editorial: Clinical Neurosciences in the Journal of Nutrition Health and Aging, L. Volicer (USA); Body Mass Index, Dementia, and Mortality in the Elderly, J.A. Luchsinger, and al. (USA); The Validity of Clinical Diagnoses of Dementia in a Group of Consecutively Autopsied Memory Clinic Patients, B.E. Gay and al. (Switzerland)
3. Geriatric Science: Evidence-based Roads to the Promotion of Health in Old Age, P. Ljubuncic and al. (Israel);
Prognosis and Vascular Co-morbidity in Dementia a Historical Cohort Study in General Practice, L. Meerman, and al. (The Netherlands); A Study of Tubular Potassium Secretory Capacity in Older Patients with Hyperkalaemia, C. Mc Greevy and al. (Ireland); Family Physicians Clinical Aptitude for the Nutritional Management of Type 2 Diabetes Mellitus in Guadalajara, Mexico, C.E. Cabrera-Pivaral, and al. (Mexico)
III - JNHA N° 3, Vol 12, 2008 contents
1. Nutrition: Dietary-Related Profile of Older Persons in the Chinese Community: An Exploratory Study, M.M.Y. Tse and al. (Hong Kong); Age Group Differences in Diet and Physical Activity-Related Behaviors among Rural Men and Women, F. Nothwehr and al. (USA); Daily Eating Events among Co-living and Single-Living, Diseased Older Men, K. Kullberg and al. (Sweden)
2. Clinical Neurosciences: Serum Brain-derived Neurotrophic Factor is Associated with Reduced Appetite in Healthy Older Adults, K. Stanek and al. (USA)
Seafood (Wild and Farmed) for the Elderly: Contribution to the Dietary Intakes of Iodine, Selenium, DHA and Vitamins B12 and D, J.M. Bourre and al. (France)
3. Clinical Trials and Aging: Editorial: Clinical Trials and Aging Section, S. Gauthier (Canada); The Under-Representation of Older People in Clinical Trials: Barriers and Potential Solutions, D.W. Habicht and al. (United-Kingdom); The GeriatricMinimum Data Set for Clinical Trials (GMDS), G. Abellan van Kan and al.on behalf of the GerontoNet Collaboration (France, United-Kingdom,The Netherlands, Italy)
4. Geriatric Science: Prevalence of Sarcopenia in the French Senior Population, J. Tichet, and al. (France); The Effects of Creatine and Whey Protein Supplementation on Body Composition in Men Aged 48 to 72 Years during Resistance Training, K.A. Eliot and al.(USA); Use of the Mini Nutritional Assessment Tool in Elderly People from Long-Term Institutions of Southeast of Brazil, L.S. Ferreira and al. (Brazil); High Vitamin B12 Level and Mortality in Elderly Inpatients, N. Salles and al. (France, Switzerland); Urinary Excretion of Fluorescent Advanced Glycation End Products (Ages) in the Elderly, M.P. De la Maza and al. (Chili, USA)
Abstracts and articles available at: www.serdi-fr.com/jnha/page.php
IV - ALL JNHA PAPERS UNTIL 2007 ARE FREE ACCESS ONLINE AND AT THE IAGG WEB SITE LINKS
To increase JNHA papers accessibility it was decided with the IAGG President office Pr Renato Guimaraes to have all jnha papers until 2007 free access online at the www.serdi-fr.com/jnha
V FORTCOMING IAGG, IANA AND EUGMS CONGRESS, WORKSHOP
· IANA (International Academy on Nutrition and Aging) Symposium on Exercise, Nutrition, Alzheimer; and on: Frailty & Sarcopenia Clinical Trials (Albuquerque, NM, USA, Hyatt Regency Tamaya Resort, August 1&2, 2008) www.healthandage.com/html/min/iananda
The next 2008 IANA research symposium will take place in Albuquerque NM, august 1 and 2, 2008 organized in conjunction with the University of New-Mexico, School of Medicine; on:
- Nutrition, Exercise and Cognitive Decline and on
- Frailty and Sarcopenia Trials
at the Hyatt Regency Tamaya Resort
The aim of the meeting is to bring together the 80 best experts in the fields. For more information on speakers and topics go to: www.healthandage.com/html/min/iananda
Oral communications and posters have to be submitted to the IANA before March 30, 2008, at: abq.iana@gmail.com. Papers presented at the meeting will be published in 2 JNHA special issues on: Sarcopenia: Clinical Trials Issues and on Nutrition, Exercise and Alzheimer
Registration contact: CMEWeb@salud.unm.edu
Program: www.serdi-fr.com/ABQ.htm
· The 1st conference clinical trials on Alzheimer’s disease (CTAD)
The 1st conference Clinical Trials on Alzheimer’s Disease (CTAD) will take place in Montpellier on 17th -19th September, 2008. This conference is jointly organized by the Montpellier and Toulouse European Alzheimer’s Disease Consortium (EADC) Centers. The aims of the meeting are to bring together the current leaders in clinical trials in Alzheimer’s Disease to discuss new results, drugs in development, and future methodological issues (disease modification, outcomes, biomarkers, health economics). A Clinical Trials Training Workshop will be organized. This will be a high-level training course designed for investigators and clinical research assistants involved in clinical trials. For additional information please visit the meeting website at http://CTAD2008.ams.fr
Proceedings will be published in the JNHA
· The IAGG world meeting Paris, July 2009 is the world event in gerontology including social, basic and clinical sciences, the call of abstracts: symposium, oral or poster communications is now open at www.gerontologyparis2009.com
Held only every four years, the IAGG (International Association of Gerontology & Geriatrics) World Congress of Gerontology & Geriatrics brings together experts in the fields of ageing from around the world. The main purpose of this world event is to discuss the latest findings in the field of ageing. The Scientific Program was created with the help of the International Scientific Committee, which consists of over 85 expert members from more than 50 different countries. The 19th edition of this congress will take place in Paris, France 5 - 9 July 2009 in the Palais des Congrs. More than 5,000 participants from around the globe are expected at the 19th IAGG World Congress. For the latest news, to give us your suggestions, please go to http://www.gerontologyparis2009.com/site/forms/noticeparticipants.php
The web site is also open for symposium, oral communication and posters submission.
· 5th Congress of the EUGMS: Geriatric medicine in a time of generational shift (Copenhagen, 3-6 September 2008)
The Congress will supply you with an update on medical and surgical treatment as well as geriatric assessment, rehabilitation and management of people with multiple diseases and functional decline. You will learn about the latest scientific, evidence-based examination and clinical practice.
For further information, please see: www.eugms2008.org
VI - IANA TASK FORCE ON FRAILTY ASSESSMENT OF OLDER PEOPLE IN CLINICAL PRACTICE
The last IANA task force was on The I.A.N.A. Task Force on Frailty assessment of older people in clinical practice
Frailty is a commonly used term indicating older persons at increased risk for adverse outcomes such as onset of disability, morbidity, institutionalisation or mortality or who experience a failure to integrate adequate responses in the face of stress. Although most physicians caring for older people recognize the importance of frailty, there is still a lack of both consensus definition and consensual clinical assessment tools. The aim of the present manuscript was to perform a comprehensive review of the definitions and assessment tools on frailty in clinical practice and research, combining evidence derived from a systematic review of literature along with an expert opinion of a European, Canadian and American Geriatric Advisory Panel (GAP). There was no consensus on a definition of frailty but there was agreement to consider frailty as a pre-disability stage. Being disability a consequence rather than the cause of frailty, frail order people do not necessary need to be disabled. The GAP considered that disability (as a consequence of frailty) should not be included in frailty definitions and assessment tools. Although no consensual assessment tool could be proposed, gait speed could represent the most suitable instrument to be implemented both in research and clinical evaluation of older people, as assessment of gait speed at usual pace is a quick, inexpensive and highly reliable measure of frailty.
G. Abellan van Kan, Y. Rolland, H. Bergman, J.E. Morley, S.B. Kritchevsky, B. Vellas on behalf of the geriatric advisory panel. The JNHA vol. 12, n° 1, 2008 p; 29-37
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